Quantitative and Qualitative Changes in the Skeletal Muscle Acetylcholinesterase Activity of <I>Oreochromis niloticus</I> Exposed to Methylparathion
Abstract
Spectrophotometric assays and histochemical tests for acetylcholinesterase activity in the epaxial skeletal muscle of maturing Oreochromis niloticus after in-vivo exposure to 0.10 mg/L methylparathion showed significant inhibition of the enzyme by the pesticide. The assays manifested enzyme inhibition, after 48 and 96 hours of exposure, of 43.19% and 56.62%, respectively. These results were confirmed by the occurrences of decreased sites of acetylcholinesterase activity in the muscle fibers as exhibited upon performance of histochemical tests.
Published
2007-09-20
Issue
Section
Articles
Submission of a manuscript implies: that the work described has not been published before (except in the form of an abstract or as part of a published lecture, review, or thesis); that it is not under consideration for publication elsewhere; that its publication has been approved by all co-authors, if any, as well as by the responsible authorities at the institute where the work has been carried out; that, if and when the manuscript is accepted for publication, the authors agree to the automatic transfer of the copyright to the publisher; that the manuscript will not be published elsewhere in any language without the consent of the copyright holders; that written permission of the copyright holder is obtained by the authors for material used from other copyrighted sources; and that any costs associated with obtaining this permission are the authors’ responsibility.